There are a lot of people who have cerebral functional disorders among elderly persons and handicapped persons.They are Alzheimer¡Çs disease, schizophrenia, ADHD and so on. In order to encourage them to attend social activities and to live their own lives, early diagnosis and early treatment is important. The purpose of this study is, therefore, to examine the availability of Eye-Sensing HMD for diagnosing cerebral functional disorders as medical screening inspection for their early diagnosis. In this paper, (1)inspection items, (2) development of measurement system, (3)accuracy of pupil diameter measurement, and (4)a pilot experiment of pupil reaction to light, are described.